Elena successfully defends her PhD Thesis

Many congratulations to Elena De Calatrava Pérez, who successfully defended her PhD
thesis titled “The Synthesis, Photophysical and Biological Evaluation of Glycosylated
Naphthalimides for Medicinal and Material Applications”. Elena was a joint PhD student of Thorri and his close collaborator Prof. Eoin Scanlan; her work was examined by Prof. John Callan, The Norbrook Chair in Pharmaceutical Science, from the School of Pharmacy & Pharmaceutical Science at Ulster University. and prof. Mike Southern as the internal examiner. It was a great occasion, which was followed by a lunch in one of our
favourite restaurants, Pig’s Ear, and a small celebration in TBSI. Elena is currently working as a postdoctoral fellow in St. James’s Hospital here in Dublin.

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Elena’s PhD was funded by the SFI and focused on the development of novel glycosylated naphthalimide structures and their application in both medicinal and material chemistry. A large part of her work focused on the use of high-resolution imaging, which was carried out in collaboration with several members of the TG group as well as in close collaboration with Dr Gavin McManus from the School of Biochemistry and Immunology here at TCD. Some of her work has been published in the RSC journals Chem Commun and most recently in the OBC. We all at TG group wish Dr De Calatrava Pérez best of luck for her future!

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Welcome back Isabel!

Isabel has returned to the group following a three month internship at Alkermes Biopharmaceutical. During the internship Isabel worked as part of the R&D Formulations department, developing formulations for new oral dose drug substances, which allowed her to get experience in early stage formulation development through to scale-up, as well as investigating the potential for  PAT (Process Analytical Technology), in the form of various spectroscopic techniques, with a view to inline process monitoring. This opportunity was made possible due to a collaboration with Tarek Zeidan (Alkermes, Waltham) on Isabel’s PhD project over the last three years. This experience will greatly benefit Isabel as well as the wider Gunnlaugsson group.

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Conferences, conferences, conferences!

It has been a busy Monday for the TG group! Today, in fact, Adam and June went to attend Macrocyclic and Supramolecular Chemistry (MASC) meeting for 2018 at Lancaster University, where they had a chance to take part in the poster sessions where they summarized their works on Aggregation Induced Emission and Naphtalimides coordination structures, respectively.

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At the same time, in Belfast, Bruno and Emanuele attended the Inorganic Ireland Symposium at Queen’s University in Belfast, where they also presented the poster on their joint work on BTA ligand-sensitized Lanthanide cyclen complexes.

 

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Bruno (left) and Emanuele (right) during the poster session at Queen’s University

Way to go!

New work on 2-picolyl derived naphthalene diimide and bis-phthalimide ligands accepted

Many congratulations to June, now in her second PhD year, who has had her paper with Chris Hawes (former member of the TG Group and now and independent lecturer at the School of Chemical and Physical Sciences, Keele University, UK, named “Crystallographic studies of 2-picolyl substituted naphthalene diimide and bis-phthalimide ligands and their supramolecular coordination chemistry”, accepted for publication in CrystEngComm (DOI: 10.1039/C8CE01756E). This work is another excellent outcome of a very fruitful collaboration between the group and Chris, based on exploring the supramolecular application of naphthalene-based building blocks with various d-metal ions, featuring extended analysis of the various complexes formed by using single crystal structure analysis, but Chris was instrumental (as well as Brendan Twamley) in training several members of the TG group in carrying out their own X-ray analysis.Cryst

Good job!

New work on the luminescent sensing of organic solvents accepted

Many congratulations to Sachi, Bruno and David, who have had their paper on the generation of highly luminescent functional solid-state material, “Self-assembled bright luminescent hierarchical materials from a tripodal benzoate antenna and heptadentate Eu(III) and Tb(III) cyclen complexes” accepted in Frontiers of Chemical Science and Engineering (Front. Chem. Sci. Eng. 2019, DOI:10.1007/s11705-018-1762-3). This work, achieved in collaboration with the Prof. Wolfgang Schmitt research group here at TCD covers the use of self-assembly between cyclen-based lanthanide (Europium and Terbium) complexes and a tripodal ligand which yields a luminescent amorphous material (red and green respectively, as shown below) that can be used for the sensing of solvents such as MeOH, CH3CN and THF.

Sachi + Bruno

Amy Lynes successfully defends her PhD Thesis

The TG group congratulates with Amy, who successfully defended her thesis, “Supramolecular soft materials and structural studies of a series of BTA and pyridine-dicarboxamide derivatives with various d-metal ions”. Amy’s thesis was examined by Prof. Jonathan Steed from Durham University.

Amy’s PhD was funded by the SFI and expanded the work of the group on BTA motif-based molecules which resulted in several paper, the most recent a ChemmCommun. We all at TG group wish together Amy best of luck for her future and whatever it will have in store for her!

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