It has been a busy Monday for the TG group! Today, in fact, Adam and June went to attend Macrocyclic and Supramolecular Chemistry (MASC) meeting for 2018 at Lancaster University, where they had a chance to take part in the poster sessions where they summarized their works on Aggregation Induced Emission and Naphtalimides coordination structures, respectively.
At the same time, in Belfast, Bruno and Emanuele attended the Inorganic Ireland Symposium at Queen’s University in Belfast, where they also presented the poster on their joint work on BTA ligand-sensitized Lanthanide cyclen complexes.
Bruno (left) and Emanuele (right) during the poster session at Queen’s University
Way to go!
Many congratulations to Trinity College Dublin team Dr. Oxana Kotova, Dr. Steve Comby, Dr. Komala Pandurangan (now at Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR)), Dr. Floriana Stomeo (now at IPSEN Pharma), Dr. John E. O’Brien and Dr. Martin Feeney who in collaboration with Dr. Robert D. Peacock from University of Glasgow and Prof. Colin P. McCoy from Queen’s University Belfast who have had their paper entitled “The effect of the linker size in C2-symmetrical chiral ligands on the self-assembly formation of luminescent triple-stranded di-metallic Eu(III) helicates in solution” accepted in Dalton Transactions.
The article discussed the formation of chiral, luminescent [Eu2:L3] assemblies with high stability constants in solution. However, it was found that the composition of the assemblies in the solid state was more complex. The chirality of the studied systems allowed us to investigate their formation using various techniques including circular dichroism and circularly polarised luminescence spectroscopies and help their development towards materials for the applications in electronics for virtual reality applications (3D screens) and in medical diagnostic.
The article is available online at: https://pubs.rsc.org/en/content/articlelanding/2018/dt/c8dt02753f#!divAbstract
On Friday 22nd June, Elena represented the Organic Chemistry Department of TCD at the annual Irish Universities Chemistry Research Colloquium at Queen’s University of Belfast, with a talk on the development of glycosylated naphthalimides as prodrugs for medicinal applications. The Colloquium, in its 70th edition, started on Thursday 21st, and highlighted the outstanding research conducted by the best young chemists at third level institutions across Ireland, involving more than 60 students between posters and oral presentations.
Great Job Elena!
Today several members of the Gunnlaugsson group attended the Irish Regional meeting for the RSC Organic Division at Queen’s University Belfast. Thorri presented some of the topics of the group in his talk, “Application of supramolecular recognition in synthesis and self-assembly formations” and Adam presented a poster about his previous work in St Andrews.
The europium-based luminescence is only quenched when urease enzymes break down urea in the solution
Many congratulations to Esther, Sam and Sandra who had their paper “Luminescent Lanthanide Cyclen-Based Enzymatic Assay Capable of Diagnosing the Onset of Catheter-Associated Urinary Tract Infections Both in Solution and within Polymeric Hydrogels” accepted in the Journal of the American Chemical Society. The work focuses on using delayed
luminescence Eu(III)-based pH-responsive probes to monitor the activity of urease, which hydrolyses urea in
aqueous solution upon onset of bacterial infection.
This system can be incorporated into soft polymeric materials such as hydrogels. The work was carried out in collaboration with Prof. Clive Williams of the School of Biochemistry and Immunology in TCD and Prof. Colin McCoy from the School of Pharmacy, Queen’s University of Belfast.