Our paper “Two-Photon Luminescent Bone Imaging Using Europium Nanoagents“, published last year in Cell Press’ journal Chem, was highlighted by the journal as one of six papers from 2016 that was of particular scientific importance. Once again, congrats to Esther and Steve on their work.
Esther’s work on cyclen-appended gold nanoparticles, which can be used to image microcracks in damaged bone, has been featured by the international news agency Reuters. The work which was published last year as a cover article in Chem, the new journal from Cell Press.
The europium-based luminescence is only quenched when urease enzymes break down urea in the solution
Many congratulations to Esther, Sam and Sandra who had their paper “Luminescent Lanthanide Cyclen-Based Enzymatic Assay Capable of Diagnosing the Onset of Catheter-Associated Urinary Tract Infections Both in Solution and within Polymeric Hydrogels” accepted in the Journal of the American Chemical Society. The work focuses on using delayed
luminescence Eu(III)-based pH-responsive probes to monitor the activity of urease, which hydrolyses urea in
aqueous solution upon onset of bacterial infection.
This system can be incorporated into soft polymeric materials such as hydrogels. The work was carried out in collaboration with Prof. Clive Williams of the School of Biochemistry and Immunology in TCD and Prof. Colin McCoy from the School of Pharmacy, Queen’s University of Belfast.
Everyone in the TG group would like to say a big thanks and goodbye to Emma and Esther for all the great work they’ve done over the past few years and for all their help when we needed it. Emma has taken on a position in Science Foundation Ireland, Ireland’s national funding body for science research. During her time here, Emma has worked on the development of various novel molecules, most notably naphthalimide-based systems. These have found use as drug delivery agents, potential anti-cancer and DNA binding agents, and sensors for biologically relevant ions.
Esther’s work on Ln(III)-cyclen complexes has led to recent publications in Inorg. Chem., Chem. Commun. and Cell Press’ new journal Chem, and she was profiled in the latter’s Potential Energy column. Esther will joining the Health Products Regulatory Authority.
We’ll miss you guys – best of luck in all your endeavors. Make sure you come back and visit us!
Huge congrats to Dr. Esther Surender on her Potential Energy article published in Chem titled “Exploring New Frontiers in Medical Diagnostics through Collaboration“. This short article discusses her PhD research project which led to the teams article “Two-Photon Luminescent Bone Imaging Using Europium Nanoagents“, as well the benefits of pursing a multidisciplinary PhD.
A small portion of Esther’s profile in Chem
Prof. Gunnlaugsson, Prof. Clive Lee, and Dr. Esther Surender were recently interviewed about their upcoming publication on bone diagnostics, which is to be featured in the Cell Press journal Chem.
Esther discusses her work at her bench!
Getting ready in the Boardroom
Thorri explaining the importance of the work