Cover feature for Elena’s work in Chemical Communications


The inside front cover designed by Elena De Calatrava-Pérez and Amparo Mérida-Navas

Many congratulation to Elena De Calatrava-Pérez on her article in Chemical Communications: Glycosidase activated release of fluorescent 1,8-naphthalimide probes for tumor cell imaging from glycosylated ‘pro-probes’ (Chem. Commun., 2016, 52, 13086-13089). The work has been featured on the cover of the journal, which was designed by Elena and her sister-in-law Amparo Mérida-Navas, a trained graphic designer. The work describes the development of fluorescent glycosylated 4-amino-1,8-naphthalimide derivatives as ‘pro-probes’ that are taken up into cancer cells upon being selectively hydrolysed in situ by glycosidase enzymes. Elena is a joint PhD student between Thorri and Prof. Eoin Scanlan in the School of Chemistry here at TCD (both based in TBSI) and the work was carried out in collaboration with Prof. Clive Williams from the School of Biochemistry and Immunology (TBSI).